Genetic and hereditary syndromes

Prader-Willi Syndrome

A genetic condition affecting development, often causing low muscle tone, intellectual disability, and chronic hunger.
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About

Prader-Willi Syndrome (PWS) is a rare genetic condition that affects physical, intellectual, and behavioural development. Key features often include low muscle tone, intellectual disability, short stature, emotional and behavioural challenges, and a chronic feeling of hunger that can lead to overeating and obesity if not managed.

This condition is often invisible.

Many disabilities, including this one, may not have outward signs—people can be significantly impacted even if they appear “fine” on the outside.

Common Challenges

  • Intellectual disability affecting learning or task comprehension
  • Difficulty with impulse control and emotional regulation
  • Challenges with attention, focus, and routine changes
  • Behavioural issues, including rigidity or anxiety
  • Food-seeking behaviours that may be inappropriate in the workplace
  • Fatigue due to low muscle tone or medical complications

Practitioner Help

  • Match work tasks to the person's cognitive and physical abilities
  • Support the development of routines and structured work environments
  • Provide behavioural support strategies and social coaching
  • Encourage communication between the employer and the support team
  • Help educate the employer on the condition and necessary boundaries

Common Accommodations

  • Extra time to learn new tasks and repetition-based training
  • Supervision or secure areas to reduce unsupervised access to food
  • Clear expectations and feedback systems
  • Job coaching or ongoing support
  • Regular breaks or access to quiet rest areas
  • Visual aids or assistive technology
View more on enableDex

Notes

With the right supports and structured environments, individuals with PWS can participate in meaningful employment. Education of coworkers and supervisors is often key to fostering understanding and success.

The last Friday of May is Go Orange day when people across the globe wear something orange in support of Prader-Willi Syndrome.

Resources

  • Prader-Willi syndrome | healthdirect
  • Prader-Willi Syndrome Association of Australia
  • Prader-Willi syndrome | About the Disease | GARD
Genetic and hereditary syndromes

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